The Practice of Medicinal Chemistry, Fourth Edition 

The Practice of Medicinal Chemistry, Fourth Edition provides a practical and comprehensive overview of the daily issues facing pharmaceutical researchers and chemists. In addition to its thorough  treatment of basic medicinal chemistry principles, this updated edition has been revised to provide new and expanded coverage of the latest technologies and approaches in drug discovery.

With topics like high content screening, scoring, docking, binding free energy calculations, polypharmacology, QSAR, chemical collections and databases, and much more, this book is the go-to reference for all academic and pharmaceutical researchers who need a complete understanding of medicinal chemistry and its application to drug discovery and development.

<药物化学实践》第四版对制药研究人员和化学家面临的日常问题进行了实用和全面的概述。除了对基本药物化学原理的透彻处理外，该更新版还对药物发现中的最新技术和方法进行了新的和扩大的报道。

本书的主题包括高含量筛选、评分、对接、结合自由能计算、多药理学、QSAR、化学文集和数据库等，是所有需要全面了解药物化学及其在药物发现和开发中的应用的学术和制药研究人员的首选参考。